ACTG

ACTG is a global clinical trials network that conducts research to improve the management of HIV and its comorbidities; develop a cure for HIV; and innovate treatments for tuberculosis, hepatitis B, and emerging infectious diseases.

All enrolling trials across our research areas have been temporarily closed to screening .

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ACTG Annual Meeting 2025 Award Winners

At ACTG, the annual memorial awards stand as enduring tributes to individuals whose names embody the very ideals and qualities that define our community. Each award honors those who have made indelible contributions to our mission, reflecting values of innovation, collaboration, and compassion in the fight against HIV and its comorbidities. These names not only symbolize excellence in research and service but also serve as inspirations for current and future generations of scientists and caregivers within the ACTG network.

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Our Areas of Research

HIV comorbidities & complications

4 enrolling trials

HIV cure

4 enrolling trials

COVID-19 and Mpox

2 enrolling trials

HIV treatment

2 enrolling trials

Tuberculosis

4 enrolling trials

Hepatitis

2 enrolling trials

Our Impact and Reach

Since our founding in 1987, ACTG investigators and sites across four continents have served as major resources for HIV and other infectious disease research, treatment, care, and education in their communities.

47k+

participants

sites

countries

3k+

trials

Our Trials Locations Worldwide

Botswana

Gaborone CRS

Brazil

Instituto de Pesquisa Clinica Evandro Chagas CRS

Instituto de Pesquisas em AIDS do Rio Grande do Sul – IPARGS CRS

Haiti

GHESKIO Institute of Infectious Diseases and Reproductive Health (GHESKIO – IMIS) CRS

Les Centres Gheskio (Gheskio-INLR) CRS

India

Byramjee Jeejeebhoy Medical College (BJMC) CRS

Kenya

Kenya Medical Research Institute/Walter Reed Project Clinical Research Center (KEMRI/WRP) CRS

Moi University Clinical Research Center (MUCRC) CRS

Malawi

Mexico

Peru

South Africa

CAPRISA eThekwini CRS

Soweto ACTG CRS

Durban International CRS

South African Tuberculosis Vaccine Initiative (SATVI) CRS

University of Cape Town Lung Institute (UCTLI) CRS

University of the Witwatersrand Helen Joseph (WITS HJH) CRS

Thailand

Chiang Mai University HIV Treatment (CMU HIV Treatment) CRS

Thai Red Cross AIDS Research Centre (TRC-ARC) CRS

Uganda

Joint Clinical Research Centre (JCRC)/Kampala CRS

MU-JHU Research Collaboration (MUJHU CARE LTD) CRS

USA

Alabama CRS

Brigham and Women’s Hospital Therapeutics (BWH TCRS) CRS

Massachusetts General Hospital (MGH) CRS

Case Clinical Research Site CRS

Cincinnati CRS

Northwestern University CRS

Columbia Physicians & Surgeons (P&S) CRS

De La Salle Health Science Institute Angelo King Medical Research Center (DLSHSI-AKMRC)

Nutrición-Mexico CRS

The Ponce de Leon Center CRS

Johns Hopkins University CRS

Ohio State University CRS

University of Pittsburgh CRS

University of California, San Francisco HIV/AIDS CRS

University of Washington Positive Research CRS

Whitman Walker Health CRS

Houston AIDS Research Team (HART) CRS

UCSD Antiviral Research Center CRS

University of Colorado Hospital CRS

Harbor University of California Los Angeles Center CRS

University of California, Los Angeles CARE Center CRS

Chapel Hill CRS

Greensboro CRS

Penn Therapeutics CRS

University of Rochester Adult HIV Therapeutic Strategies Network CRS

Vanderbilt Therapeutics (VT) CRS

Washington University Therapeutics (WT) CRS

New Jersey Medical School Clinical Research Center CRS

Weill Cornell Chelsea CRS

Weill Cornell Uptown CRS

Vietnam

Hanoi Medical University (HMU)

Zimbabwe

Milton Park CRS

Voices for the Community

jankosmyna@gmail.com

Jan Kosmyna, MIS, B.Ed., RN

North Royalton, Ohio

Maureen Phiri

CAB member

Mandisa Jwara

CAB member

Roseline Swartz

CAB member

ANNOUNCEMENTS

ACTG Annual Meeting 2025 Award Winners

29 July 2025

ACTG Presents Study at CROI Demonstrating Increased Risk of Obesity and Cardiometabolic Disease After Switch to Integrase Inhibitor-Containing Regimen

17 March 2025

ACTG Presents Important Findings from REPRIEVE at CROI 2025

17 March 2025

LATEST NEWSLETTER

July 2025

World Hepatitis Day, Annual Meeting Awardees, an interview with Dr. Doug Richman and more.

Previous Issues

Red Ribbon Registry

The Red Ribbon Registry is a database of volunteers who are interested in participating in HIV/AIDS clinical trials.

Learn more here!